A Genomic Toolkit for the Mechanistic Dissection of Intractable Human Gut Bacteria.

Despite the remarkable microbial diversity found within humans, our ability to link genes to phenotypes is based upon a handful of model microorganisms. We report a comparative genomics platform for Eggerthella lenta and other Coriobacteriia, a neglected taxon broadly relevant to human health and disease.

We uncover extensive genetic and metabolic diversity and validate a tool for mapping phenotypes to genes and sequence variants. We also present a tool for the quantification of strains from metagenomic sequencing data, enabling the identification of genes that predict bacterial fitness. Competitive growth is reproducible under laboratory conditions and attributable to intrinsic growth rates and resource utilization.

T16Ainh - A01

B5635-10 10 mg
EUR 116

T16Ainh - A01

B5635-50 50 mg
EUR 311

CaCCinh-A01

B5747-10 10 mg
EUR 193

CaCCinh-A01

B5747-25 25 mg
EUR 387

CaCCinh-A01

B5747-5 5 mg
EUR 125

CaCCinh-A01

B5747-50 50 mg
EUR 614

CaCCinh-A01

HY-100611 50mg
EUR 519

Smurf1-IN-A01

HY-110195 10mg
EUR 223

AZIDE BLOOD AGAR BASE

A01-113-10kg 10 kg
EUR 2532

AZIDE BLOOD AGAR BASE

A01-113-2kg 2kg
EUR 589

AZIDE BLOOD AGAR BASE

A01-113-500g 500 g
EUR 197

JIB-04

B1579-20 20 mg
EUR 209
Description: JIB-04 is a small molecule inhibitor of Jumonji histone demethylase with IC50 values of [1].JIB-04 is a pyridine hydrazone. It is a pan -selective inhibitor of Jumonji histone demethylases.

JIB-04

B1579-5.1 10 mM (in 1mL DMSO)
EUR 154
Description: JIB-04 is a small molecule inhibitor of Jumonji histone demethylase with IC50 values of [1].JIB-04 is a pyridine hydrazone. It is a pan -selective inhibitor of Jumonji histone demethylases.

JIB-04

B1579-50 50 mg
EUR 350
Description: JIB-04 is a small molecule inhibitor of Jumonji histone demethylase with IC50 values of [1].JIB-04 is a pyridine hydrazone. It is a pan -selective inhibitor of Jumonji histone demethylases.

JIB-04

HY-13953 50mg
EUR 457

Ro 04-6790

B7216-10 10 mg
EUR 318

Ro 04-6790

B7216-50 50 mg
EUR 1178

155734-04-6

TBZ1243 unit Ask for price

LB (Lennox)

113 500 ml
EUR 63

Ro 04-5595 hydrochloride

B6919-10 10 mg
EUR 340

Ro 04-5595 hydrochloride

B6919-50 50 mg
EUR 1276

FMF-04-159-2

HY-127104 25mg
EUR 1187

HG-14-10-04

HY-15801 100mg
EUR 2943

Anti-LYK5 (4.00E+04)

YF-MA11717 100 ug
EUR 363
Description: Mouse monoclonal to LYK5

CREB327 (113 - 126)

5-01003 4 x 5mg Ask for price

pVITRO1-SS-113

PVT18241 2 ug
EUR 300

Monoclonal ICAM3 / CD50 Antibody (clone MEM-04, Azide-free), Clone: MEM-04

APR16798G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human ICAM3 / CD50 (clone MEM-04, Azide-free). The antibodies are raised in Mouse and are from clone MEM-04. This antibody is applicable in IHC-P, Flo, Func

Monoclonal KRT18 / CK18 / Cytokeratin 18 Antibody (clone C-04), Clone: C-04

APR17085G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human KRT18 / CK18 / Cytokeratin 18 (clone C-04). The antibodies are raised in Mouse and are from clone C-04. This antibody is applicable in WB and IHC-P, ICC, E, IP, Flo

Jumonji HDM Inhibitor, JIB-04

2474-25
EUR 457

Jumonji HDM Inhibitor, JIB-04

2474-5
EUR 153

Cytokeratin 18(C-04) Antibody

BNUB0041-100 100uL
EUR 209
Description: Primary antibody against Cytokeratin 18(C-04), Concentration: 0.2mg/mL

Cytokeratin 18(C-04) Antibody

BNUB0041-500 500uL
EUR 458
Description: Primary antibody against Cytokeratin 18(C-04), Concentration: 0.2mg/mL

Cytokeratin 18(C-04) Antibody

BNUM0041-50 50uL
EUR 395
Description: Primary antibody against Cytokeratin 18(C-04), 1mg/mL

Cytokeratin 18(C-04) Antibody

BNC040041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF405S conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC040041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF405S conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC610041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF660R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC610041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF660R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC470041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF647 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC470041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF647 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC550041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF555 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC550041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF555 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC050041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF405M conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC050041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF405M conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC400041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF640R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC400041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF640R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC430041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF543 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC430041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF543 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC800041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF680 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC800041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF680 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC810041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF680R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC810041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF680R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNCP0041-250 250uL
EUR 383
Description: Primary antibody against Cytokeratin 18(C-04), PerCP conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNCR0041-250 250uL
EUR 383
Description: Primary antibody against Cytokeratin 18(C-04), RPE conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNCA0041-250 250uL
EUR 383
Description: Primary antibody against Cytokeratin 18(C-04), APC conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNCAP0041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNCAP0041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNCH0041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNCH0041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC940041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF594 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC940041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF594 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC700041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF770 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC700041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF770 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNCB0041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), Biotin conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNCB0041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), Biotin conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC880041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF488A conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC880041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF488A conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC680041-100 100uL
EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF568 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody

BNC680041-500 500uL
EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF568 conjugate, Concentration: 0.1mg/mL

Monoclonal KRT18 / CK18 / Cytokeratin 18 Antibody (clone C-04, Biotin), Clone: C-04

APR17086G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human KRT18 / CK18 / Cytokeratin 18 (clone C-04, Biotin). The antibodies are raised in Mouse and are from clone C-04. This antibody is applicable in IHC-P, Flo

PRKAR2B (Ab-113) Antibody

CSB-PA050526-
EUR 335
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific
  • Show more
Description: A polyclonal antibody against PRKAR2B (Ab-113). Recognizes PRKAR2B (Ab-113) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

PRKAR2B (Ab-113) Antibody

CSB-PA050526-100ul 100ul
EUR 316
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific
  • Show more
Description: A polyclonal antibody against PRKAR2B (Ab-113). Recognizes PRKAR2B (Ab-113) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

CREB327 (113 126) Peptide

20-abx266454
  • EUR 551.00
  • EUR 926.00
  • EUR 398.00
  • 10 mg
  • 25 mg
  • 5 mg
  • Shipped within 5-10 working days.

Influenza B Virus Malaysia 2506/04

7-07915 10µg Ask for price

Influenza B Virus Malaysia 2506/04

7-07916 50µg Ask for price

Influenza B Virus Malaysia 2506/04

7-07917 1mg Ask for price

Influenza B Virus Florida 07/04

7-07918 10µg Ask for price

Influenza B Virus Florida 07/04

7-07919 50µg Ask for price

Influenza B Virus Florida 07/04

7-07920 1mg Ask for price

Influenza B Virus Florida 04/06

7-07921 10µg Ask for price

Influenza B Virus Florida 04/06

7-07922 50µg Ask for price

Influenza B Virus Florida 04/06

7-07923 1mg Ask for price

Inactivated IBV Antigen (Malaysia 2506/04)

VAng-Lsx0361-inquire inquire Ask for price
Description: IBV (Malaysia 2506/04), native virus from Embryonated egg.

Inactivated IBV Antigen (Florida 07/04)

VAng-Lsx0362-inquire inquire Ask for price
Description: IBV (Florida 07/04), native virus from Embryonated egg.

Inactivated IBV Antigen (Florida 04/06)

VAng-Lsx0363-inquire inquire Ask for price
Description: IBV (Florida 04/06), native virus from Embryonated egg.

Adenovirus antibody (FITC)

60-A01 1 ml
EUR 367
Description: Goat polyclonal Adenovirus antibody (FITC) conjugated

PKA-R2β (Ab-113) Antibody

33161-100ul 100ul
EUR 252

PKA-R2β (Ab-113) Antibody

33161-50ul 50ul
EUR 187

Polyclonal ARF6 Antibody (aa84-113)

APR14999G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ARF6 (aa84-113). This antibody is tested and proven to work in the following applications:

Mitochondrial Marker(113-1) Antibody

BNUB0739-100 100uL
EUR 209
Description: Primary antibody against Mitochondrial Marker(113-1), Concentration: 0.2mg/mL

Mitochondrial Marker(113-1) Antibody

BNUB0739-500 500uL
EUR 458
Description: Primary antibody against Mitochondrial Marker(113-1), Concentration: 0.2mg/mL

Mitochondrial Marker(113-1) Antibody

BNUM0739-50 50uL
EUR 395
Description: Primary antibody against Mitochondrial Marker(113-1), 1mg/mL

Mitochondrial Marker(113-1) Antibody

BNC040739-100 100uL
EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), CF405S conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody

BNC040739-500 500uL
EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), CF405S conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody

BNC550739-100 100uL
EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), CF555 conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody

BNC550739-500 500uL
EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), CF555 conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody

BNC610739-100 100uL
EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), CF660R conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody

BNC610739-500 500uL
EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), CF660R conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody

BNC470739-100 100uL
EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), CF647 conjugate, Concentration: 0.1mg/mL

Unique signatures of in vivo competition in gnotobiotic mice include an adhesin enriched in poor colonizers. Together, these computational and experimental resources represent a strong foundation for the continued mechanistic dissection of the Coriobacteriia and a template that can be applied to study other genetically intractable taxa.