A Genomic Toolkit for the Mechanistic Dissection of Intractable Human Gut Bacteria.

Despite the remarkable microbial diversity found within humans, our ability to link genes to phenotypes is based upon a handful of model microorganisms. We report a comparative genomics platform for Eggerthella lenta and other Coriobacteriia, a neglected taxon broadly relevant to human health and disease.

We uncover extensive genetic and metabolic diversity and validate a tool for mapping phenotypes to genes and sequence variants. We also present a tool for the quantification of strains from metagenomic sequencing data, enabling the identification of genes that predict bacterial fitness. Competitive growth is reproducible under laboratory conditions and attributable to intrinsic growth rates and resource utilization.

T16Ainh - A01
B5635-10	ApexBio	10 mg	EUR 116.00

T16Ainh - A01
B5635-50	ApexBio	50 mg	EUR 311.00

CaCCinh-A01
B5747-10	ApexBio	10 mg	EUR 193.00

CaCCinh-A01
B5747-25	ApexBio	25 mg	EUR 387.00

CaCCinh-A01
B5747-5	ApexBio	5 mg	EUR 125.00

CaCCinh-A01
B5747-50	ApexBio	50 mg	EUR 614.00

CaCCinh-A01
HY-100611	MedChemExpress	50mg	EUR 519.00

Smurf1-IN-A01
HY-110195	MedChemExpress	10mg	EUR 223.00

AZIDE BLOOD AGAR BASE
A01-113-10kg	Alphabiosciences	10 kg	EUR 2532.00

AZIDE BLOOD AGAR BASE
A01-113-2kg	Alphabiosciences	2kg	EUR 589.00

AZIDE BLOOD AGAR BASE
A01-113-500g	Alphabiosciences	500 g	EUR 197.00

JIB-04
B1579-20	ApexBio	20 mg	EUR 209.00
Description: JIB-04 is a small molecule inhibitor of Jumonji histone demethylase with IC50 values of [1].JIB-04 is a pyridine hydrazone. It is a pan -selective inhibitor of Jumonji histone demethylases.

JIB-04
B1579-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 154.00
Description: JIB-04 is a small molecule inhibitor of Jumonji histone demethylase with IC50 values of [1].JIB-04 is a pyridine hydrazone. It is a pan -selective inhibitor of Jumonji histone demethylases.

JIB-04
B1579-50	ApexBio	50 mg	EUR 350.00
Description: JIB-04 is a small molecule inhibitor of Jumonji histone demethylase with IC50 values of [1].JIB-04 is a pyridine hydrazone. It is a pan -selective inhibitor of Jumonji histone demethylases.

JIB-04
HY-13953	MedChemExpress	50mg	EUR 457.00

Ro 04-6790
B7216-10	ApexBio	10 mg	EUR 318.00

Ro 04-6790
B7216-50	ApexBio	50 mg	EUR 1178.00

155734-04-6
TBZ1243	ChemNorm	unit	Ask for price

LB (Lennox)
113	AthenaES	500 ml	EUR 63.00

Ro 04-5595 hydrochloride
B6919-10	ApexBio	10 mg	EUR 340.00

Ro 04-5595 hydrochloride
B6919-50	ApexBio	50 mg	EUR 1276.00

FMF-04-159-2
HY-127104	MedChemExpress	25mg	EUR 1187.00

HG-14-10-04
HY-15801	MedChemExpress	100mg	EUR 2943.00

Anti-LYK5 (4.00E+04)
YF-MA11717	Abfrontier	100 ug	EUR 363.00
Description: Mouse monoclonal to LYK5

CREB327 (113 - 126)
5-01003	CHI Scientific	4 x 5mg	Ask for price

pVITRO1-SS-113
PVT18241	Lifescience Market	2 ug	EUR 300.00

Monoclonal ICAM3 / CD50 Antibody (clone MEM-04, Azide-free), Clone: MEM-04
APR16798G	Leading Biology	0.05mg	EUR 484.00
Description: A Monoclonal antibody against Human ICAM3 / CD50 (clone MEM-04, Azide-free). The antibodies are raised in Mouse and are from clone MEM-04. This antibody is applicable in IHC-P, Flo, Func

Monoclonal KRT18 / CK18 / Cytokeratin 18 Antibody (clone C-04), Clone: C-04
APR17085G	Leading Biology	0.05mg	EUR 484.00
Description: A Monoclonal antibody against Human KRT18 / CK18 / Cytokeratin 18 (clone C-04). The antibodies are raised in Mouse and are from clone C-04. This antibody is applicable in WB and IHC-P, ICC, E, IP, Flo

Jumonji HDM Inhibitor, JIB-04
2474-25	Biovision		EUR 457.00

Jumonji HDM Inhibitor, JIB-04
2474-5	Biovision		EUR 153.00

Cytokeratin 18(C-04) Antibody
BNUB0041-100	Biotium	100uL	EUR 209.00
Description: Primary antibody against Cytokeratin 18(C-04), Concentration: 0.2mg/mL

Cytokeratin 18(C-04) Antibody
BNUB0041-500	Biotium	500uL	EUR 458.00
Description: Primary antibody against Cytokeratin 18(C-04), Concentration: 0.2mg/mL

Cytokeratin 18(C-04) Antibody
BNUM0041-50	Biotium	50uL	EUR 395.00
Description: Primary antibody against Cytokeratin 18(C-04), 1mg/mL

Cytokeratin 18(C-04) Antibody
BNC040041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), CF405S conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC040041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), CF405S conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC610041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), CF660R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC610041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), CF660R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC470041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), CF647 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC470041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), CF647 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC550041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), CF555 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC550041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), CF555 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC050041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), CF405M conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC050041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), CF405M conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC400041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), CF640R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC400041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), CF640R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC430041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), CF543 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC430041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), CF543 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC800041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), CF680 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC800041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), CF680 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC810041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), CF680R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC810041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), CF680R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCP0041-250	Biotium	250uL	EUR 383.00
Description: Primary antibody against Cytokeratin 18(C-04), PerCP conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCR0041-250	Biotium	250uL	EUR 383.00
Description: Primary antibody against Cytokeratin 18(C-04), RPE conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCA0041-250	Biotium	250uL	EUR 383.00
Description: Primary antibody against Cytokeratin 18(C-04), APC conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCAP0041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCAP0041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCH0041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCH0041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC940041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), CF594 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC940041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), CF594 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC700041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), CF770 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC700041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), CF770 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCB0041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), Biotin conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCB0041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), Biotin conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC880041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), CF488A conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC880041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), CF488A conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC680041-100	Biotium	100uL	EUR 199.00
Description: Primary antibody against Cytokeratin 18(C-04), CF568 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC680041-500	Biotium	500uL	EUR 544.00
Description: Primary antibody against Cytokeratin 18(C-04), CF568 conjugate, Concentration: 0.1mg/mL

Monoclonal KRT18 / CK18 / Cytokeratin 18 Antibody (clone C-04, Biotin), Clone: C-04
APR17086G	Leading Biology	0.05mg	EUR 484.00
Description: A Monoclonal antibody against Human KRT18 / CK18 / Cytokeratin 18 (clone C-04, Biotin). The antibodies are raised in Mouse and are from clone C-04. This antibody is applicable in IHC-P, Flo

PRKAR2B (Ab-113) Antibody
CSB-PA050526-	Cusabio		EUR 335.00
Form: liquid Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific Show more
Description: A polyclonal antibody against PRKAR2B (Ab-113). Recognizes PRKAR2B (Ab-113) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

PRKAR2B (Ab-113) Antibody
CSB-PA050526-100ul	Cusabio	100ul	EUR 316.00
Form: liquid Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific Show more
Description: A polyclonal antibody against PRKAR2B (Ab-113). Recognizes PRKAR2B (Ab-113) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

CREB327 (113 126) Peptide
20-abx266454	Abbexa	EUR 551.00 EUR 926.00 EUR 398.00	0 1 2
Shipped within 5-10 working days.

Influenza B Virus Malaysia 2506/04
7-07915	CHI Scientific	10µg	Ask for price

Influenza B Virus Malaysia 2506/04
7-07916	CHI Scientific	50µg	Ask for price

Influenza B Virus Malaysia 2506/04
7-07917	CHI Scientific	1mg	Ask for price

Influenza B Virus Florida 07/04
7-07918	CHI Scientific	10µg	Ask for price

Influenza B Virus Florida 07/04
7-07919	CHI Scientific	50µg	Ask for price

Influenza B Virus Florida 07/04
7-07920	CHI Scientific	1mg	Ask for price

Influenza B Virus Florida 04/06
7-07921	CHI Scientific	10µg	Ask for price

Influenza B Virus Florida 04/06
7-07922	CHI Scientific	50µg	Ask for price

Influenza B Virus Florida 04/06
7-07923	CHI Scientific	1mg	Ask for price

Inactivated IBV Antigen (Malaysia 2506/04)
VAng-Lsx0361-inquire	Creative Biolabs	inquire	Ask for price
Description: IBV (Malaysia 2506/04), native virus from Embryonated egg.

Inactivated IBV Antigen (Florida 07/04)
VAng-Lsx0362-inquire	Creative Biolabs	inquire	Ask for price
Description: IBV (Florida 07/04), native virus from Embryonated egg.

Inactivated IBV Antigen (Florida 04/06)
VAng-Lsx0363-inquire	Creative Biolabs	inquire	Ask for price
Description: IBV (Florida 04/06), native virus from Embryonated egg.

Adenovirus antibody (FITC)
60-A01	Fitzgerald	1 ml	EUR 367.00
Description: Goat polyclonal Adenovirus antibody (FITC) conjugated

Anti-P.fluorescens HCP
7-04	Cygnus Technologies	1 ml	EUR 334.00
Product category: Antibodies
Description: Anti-P.fluorescens HCP by Cygnus Technologies is available in Europe via Gentaur.

Rabbit anti-Rift Valley Fever (RVFV) pAb
04-0001	IBT Bioservices	500ug	EUR 257.00
Description: Related to: Other Viruses Applications: ELISA, WB

Rabbit anti-Venezuelan Equine Encephalitis (VEE) pAb
04-0002	IBT Bioservices	500ug	EUR 257.00
Description: Related to: Alphaviruses Applications: ELISA, WB

Rabbit anti-MARV VLP pAb
04-0005	IBT Bioservices	500ug	EUR 253.00
Description: Related to: Filoviruses Applications: ELISA, WB

Rabbit anti-Junin pAb
04-0006	IBT Bioservices	500ug	EUR 257.00
Description: Related to: Other Viruses Applications: ELISA, WB

Rabbit anti-Chikungunya (CHIKV) pAb
04-0008	IBT Bioservices	500ug	EUR 293.00
Description: Related to: Alphaviruses Applications: ELISA, WB

Rabbit anti-LukS-PV pAb
04-0009	IBT Bioservices	500ug	EUR 354.00
Description: Related to: Staphylococcus Applications: ELISA, WB

Rabbit anti-Hla pAb
04-0010	IBT Bioservices	500ug	EUR 303.00
Description: Related to: Staphylococcus Applications: ELISA, WB

Rabbit anti-CCHFV N protein pAb
04-0011	IBT Bioservices	100ug	EUR 476.00
Description: Related to: Other Viruses Applications: ELISA, WB

50ml TC Tubes, Conical, 440 units/box
04-5540150	Gentaur Genprice	440 units/box	EUR 71.00

Nitrocellulose Membrane, 0.45 µm, 9 cm x 10cm
AR0135-04	BosterBio	20 sheets/Pack	EUR 96.00

Catalase (>40,000 u/mg), Bovine Liver
CAT-04	Alpha Diagnostics	1 mg	EUR 286.00

Advanced Medium
C0003-04	Addexbio	RT 500 mL Bottle	EUR 103.00

b-Glucuronidase (1000 U/mg), Helix pomatia, freeze dried material
BGS-04	Alpha Diagnostics	5 mU	EUR 651.00

Alkaline Phosphatase (1000 Glycine U/mg protein), Calf Intestine
ALP-04	Alpha Diagnostics	25 mg	EUR 469.00

Glucose Oxidase (300 U/mg), Aspergillus Niger
GOX-04	Alpha Diagnostics	2 mU	EUR 590.00

2 × Rapid Taq Master Mix
P222-04	Vazyme	50 ml (10×5ml)	EUR 257.00

Lactate dehydrogenase (~200 U/mg), Human Muscle
LDH-04	Alpha Diagnostics	100 U	EUR 651.00

12 Well Comb ,1mm Thick For Enduro 10cm Gel System
LE1000C10-04	GenDepot	Ea	EUR 128.00

14 Well Comb ,1mm Thick For Enduro 15cm Gel System
LE1000C15-04	GenDepot	Ea	EUR 131.00

20 Well Mc Comb ,1.5mm Thick For Enduro 20cm Gel System
LE1000C20-04	GenDepot	Ea	EUR 138.00

12 Well Mc Comb , 1.5mm Thick For Enduro 7cm Gel System
LE1000C7-04	GenDepot	Ea	EUR 124.00

Casting Dams, For Enduro 20cm Gel System
LE1000CD-04	GenDepot	Ea	EUR 192.00

Gel Tray 15 X 10 Cm
LE1000GT-04	GenDepot	Ea	EUR 151.00

VAHTS AmpSeq Adapters 25-96 for Illumina (49-72)
NA111-04	Vazyme	12 x 10 rxn	EUR 1064.00

VAHTS AmpSeq Adapters 25-96 for Ion Torrent (49-72)
NA121-04	Vazyme	12 x 10 rxn	EUR 1064.00

Unique signatures of in vivo competition in gnotobiotic mice include an adhesin enriched in poor colonizers. Together, these computational and experimental resources represent a strong foundation for the continued mechanistic dissection of the Coriobacteriia and a template that can be applied to study other genetically intractable taxa.