A Genomic Toolkit for the Mechanistic Dissection of Intractable Human Gut Bacteria.

Despite the remarkable microbial diversity found within humans, our ability to link genes to phenotypes is based upon a handful of model microorganisms. We report a comparative genomics platform for Eggerthella lenta and other Coriobacteriia, a neglected taxon broadly relevant to human health and disease.

We uncover extensive genetic and metabolic diversity and validate a tool for mapping phenotypes to genes and sequence variants. We also present a tool for the quantification of strains from metagenomic sequencing data, enabling the identification of genes that predict bacterial fitness. Competitive growth is reproducible under laboratory conditions and attributable to intrinsic growth rates and resource utilization.

CaCCinh-A01
B5747-25	ApexBio	25 mg	EUR 387

CaCCinh-A01
B5747-5	ApexBio	5 mg	EUR 125

CaCCinh-A01
B5747-50	ApexBio	50 mg	EUR 614

CaCCinh-A01
B2014-25	Biovision		EUR 544

CaCCinh-A01
B2014-5	Biovision		EUR 175

Smurf1-IN-A01
HY-110195	MedChemExpress	10mg	EUR 223

AZIDE BLOOD AGAR BASE
A01-113-10kg	Alphabiosciences	10 kg	EUR 2532

AZIDE BLOOD AGAR BASE
A01-113-2kg	Alphabiosciences	2kg	EUR 589

AZIDE BLOOD AGAR BASE
A01-113-500g	Alphabiosciences	500 g	EUR 197

JIB-04
HY-13953	MedChemExpress	50mg	EUR 457

JIB-04
B1579-20	ApexBio	20 mg	EUR 209
Description: JIB-04 is a small molecule inhibitor of Jumonji histone demethylase with IC50 values of [1].JIB-04 is a pyridine hydrazone. It is a pan -selective inhibitor of Jumonji histone demethylases.

JIB-04
B1579-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 154
Description: JIB-04 is a small molecule inhibitor of Jumonji histone demethylase with IC50 values of [1].JIB-04 is a pyridine hydrazone. It is a pan -selective inhibitor of Jumonji histone demethylases.

JIB-04
B1579-50	ApexBio	50 mg	EUR 350
Description: JIB-04 is a small molecule inhibitor of Jumonji histone demethylase with IC50 values of [1].JIB-04 is a pyridine hydrazone. It is a pan -selective inhibitor of Jumonji histone demethylases.

Ro 04-6790
B7216-10	ApexBio	10 mg	EUR 318

Ro 04-6790
B7216-50	ApexBio	50 mg	EUR 1178

155734-04-6
TBZ1243	ChemNorm	unit	Ask for price

Sulfo-Cyanine3 tetrazine, 1 mg
113	Lumiprobe	1 mg	EUR 108

HG-14-10-04
HY-15801	MedChemExpress	100mg	EUR 2943

FMF-04-159-2
HY-127104	MedChemExpress	25mg	EUR 1187

Ro 04-5595 hydrochloride
B6919-10	ApexBio	10 mg	EUR 340

Ro 04-5595 hydrochloride
B6919-50	ApexBio	50 mg	EUR 1276

Anti-LYK5 (4.00E+04)
YF-MA11717	Abfrontier	100 ug	EUR 363
Description: Mouse monoclonal to LYK5

CREB327 (113 - 126)
5-01003	CHI Scientific	4 x 5mg	Ask for price

pVITRO1-SS-113
PVT18241	Lifescience Market	2 ug	EUR 300

Monoclonal ICAM3 / CD50 Antibody (clone MEM-04, Azide-free), Clone: MEM-04
APR16798G	Leading Biology	0.05mg	EUR 484
Description: A Monoclonal antibody against Human ICAM3 / CD50 (clone MEM-04, Azide-free). The antibodies are raised in Mouse and are from clone MEM-04. This antibody is applicable in IHC-P, Flo, Func

Monoclonal KRT18 / CK18 / Cytokeratin 18 Antibody (clone C-04), Clone: C-04
APR17085G	Leading Biology	0.05mg	EUR 484
Description: A Monoclonal antibody against Human KRT18 / CK18 / Cytokeratin 18 (clone C-04). The antibodies are raised in Mouse and are from clone C-04. This antibody is applicable in WB and IHC-P, ICC, E, IP, Flo

Cytokeratin 18(C-04) Antibody
BNC040041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF405S conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC040041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF405S conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC470041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF647 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC470041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF647 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC550041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF555 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC550041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF555 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCB0041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), Biotin conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCB0041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), Biotin conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC810041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF680R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC810041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF680R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC700041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF770 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC700041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF770 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC880041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF488A conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC880041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF488A conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC940041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF594 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC940041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF594 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC680041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF568 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC680041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF568 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCA0041-250	Biotium	250uL	EUR 383
Description: Primary antibody against Cytokeratin 18(C-04), APC conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCAP0041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCAP0041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNUM0041-50	Biotium	50uL	EUR 395
Description: Primary antibody against Cytokeratin 18(C-04), 1mg/mL

Cytokeratin 18(C-04) Antibody
BNCP0041-250	Biotium	250uL	EUR 383
Description: Primary antibody against Cytokeratin 18(C-04), PerCP conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC050041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF405M conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC050041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF405M conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC400041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF640R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC400041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF640R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCR0041-250	Biotium	250uL	EUR 383
Description: Primary antibody against Cytokeratin 18(C-04), RPE conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNUB0041-100	Biotium	100uL	EUR 209
Description: Primary antibody against Cytokeratin 18(C-04), Concentration: 0.2mg/mL

Cytokeratin 18(C-04) Antibody
BNUB0041-500	Biotium	500uL	EUR 458
Description: Primary antibody against Cytokeratin 18(C-04), Concentration: 0.2mg/mL

Cytokeratin 18(C-04) Antibody
BNC430041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF543 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC430041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF543 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCH0041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNCH0041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC610041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF660R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC610041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF660R conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC800041-100	Biotium	100uL	EUR 199
Description: Primary antibody against Cytokeratin 18(C-04), CF680 conjugate, Concentration: 0.1mg/mL

Cytokeratin 18(C-04) Antibody
BNC800041-500	Biotium	500uL	EUR 544
Description: Primary antibody against Cytokeratin 18(C-04), CF680 conjugate, Concentration: 0.1mg/mL

Jumonji HDM Inhibitor, JIB-04
2474-25	Biovision		EUR 457

Jumonji HDM Inhibitor, JIB-04
2474-5	Biovision		EUR 153

Monoclonal KRT18 / CK18 / Cytokeratin 18 Antibody (clone C-04, Biotin), Clone: C-04
APR17086G	Leading Biology	0.05mg	EUR 484
Description: A Monoclonal antibody against Human KRT18 / CK18 / Cytokeratin 18 (clone C-04, Biotin). The antibodies are raised in Mouse and are from clone C-04. This antibody is applicable in IHC-P, Flo

PRKAR2B (Ab-113) Antibody
CSB-PA050526-	Cusabio		EUR 335
Description: A polyclonal antibody against PRKAR2B (Ab-113). Recognizes PRKAR2B (Ab-113) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

PRKAR2B (Ab-113) Antibody
CSB-PA050526-100ul	Cusabio	100ul	EUR 316
Description: A polyclonal antibody against PRKAR2B (Ab-113). Recognizes PRKAR2B (Ab-113) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

CREB327 (113 126) Peptide
20-abx266454	Abbexa	EUR 551.00 EUR 926.00 EUR 398.00	10 mg 25 mg 5 mg

Inactivated IBV Antigen (Malaysia 2506/04)
VAng-Lsx0361-inquire	Creative Biolabs	inquire	Ask for price
Description: IBV (Malaysia 2506/04), native virus from Embryonated egg.

Inactivated IBV Antigen (Florida 07/04)
VAng-Lsx0362-inquire	Creative Biolabs	inquire	Ask for price
Description: IBV (Florida 07/04), native virus from Embryonated egg.

Inactivated IBV Antigen (Florida 04/06)
VAng-Lsx0363-inquire	Creative Biolabs	inquire	Ask for price
Description: IBV (Florida 04/06), native virus from Embryonated egg.

Influenza B Virus Malaysia 2506/04
7-07915	CHI Scientific	10µg	Ask for price

Influenza B Virus Malaysia 2506/04
7-07916	CHI Scientific	50µg	Ask for price

Influenza B Virus Malaysia 2506/04
7-07917	CHI Scientific	1mg	Ask for price

Influenza B Virus Florida 07/04
7-07918	CHI Scientific	10µg	Ask for price

Influenza B Virus Florida 07/04
7-07919	CHI Scientific	50µg	Ask for price

Influenza B Virus Florida 07/04
7-07920	CHI Scientific	1mg	Ask for price

Influenza B Virus Florida 04/06
7-07921	CHI Scientific	10µg	Ask for price

Influenza B Virus Florida 04/06
7-07922	CHI Scientific	50µg	Ask for price

Influenza B Virus Florida 04/06
7-07923	CHI Scientific	1mg	Ask for price

Recombinant Defensin Beta 113 (DEFb113)
4-RPQ649Hu01	Cloud-Clone	EUR 583.84 EUR 259.00 EUR 1914.40 EUR 704.80 EUR 1309.60 EUR 454.00 EUR 4636.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Defensin Beta 113 expressed in: E.coli

Polyclonal ARF6 Antibody (aa84-113)
APR14999G	Leading Biology	0.05mg	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ARF6 (aa84-113). This antibody is tested and proven to work in the following applications:

PKA-R2β (Ab-113) Antibody
33161-100ul	SAB	100ul	EUR 252

PKA-R2β (Ab-113) Antibody
33161-50ul	SAB	50ul	EUR 187

Mitochondrial Marker(113-1) Antibody
BNC040739-100	Biotium	100uL	EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), CF405S conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC040739-500	Biotium	500uL	EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), CF405S conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC470739-100	Biotium	100uL	EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), CF647 conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC470739-500	Biotium	500uL	EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), CF647 conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNCAP0739-100	Biotium	100uL	EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNCAP0739-500	Biotium	500uL	EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNCB0739-100	Biotium	100uL	EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), Biotin conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNCB0739-500	Biotium	500uL	EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), Biotin conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC810739-100	Biotium	100uL	EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), CF680R conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC810739-500	Biotium	500uL	EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), CF680R conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC700739-100	Biotium	100uL	EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), CF770 conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC700739-500	Biotium	500uL	EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), CF770 conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC880739-100	Biotium	100uL	EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), CF488A conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC880739-500	Biotium	500uL	EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), CF488A conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC610739-100	Biotium	100uL	EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), CF660R conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC610739-500	Biotium	500uL	EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), CF660R conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC680739-100	Biotium	100uL	EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), CF568 conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC680739-500	Biotium	500uL	EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), CF568 conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNCA0739-250	Biotium	250uL	EUR 383
Description: Primary antibody against Mitochondrial Marker(113-1), APC conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNUM0739-50	Biotium	50uL	EUR 395
Description: Primary antibody against Mitochondrial Marker(113-1), 1mg/mL

Mitochondrial Marker(113-1) Antibody
BNCP0739-250	Biotium	250uL	EUR 383
Description: Primary antibody against Mitochondrial Marker(113-1), PerCP conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC050739-100	Biotium	100uL	EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), CF405M conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC050739-500	Biotium	500uL	EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), CF405M conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC400739-100	Biotium	100uL	EUR 199
Description: Primary antibody against Mitochondrial Marker(113-1), CF640R conjugate, Concentration: 0.1mg/mL

Mitochondrial Marker(113-1) Antibody
BNC400739-500	Biotium	500uL	EUR 544
Description: Primary antibody against Mitochondrial Marker(113-1), CF640R conjugate, Concentration: 0.1mg/mL

Unique signatures of in vivo competition in gnotobiotic mice include an adhesin enriched in poor colonizers. Together, these computational and experimental resources represent a strong foundation for the continued mechanistic dissection of the Coriobacteriia and a template that can be applied to study other genetically intractable taxa.